文档介绍：zy@ 中医临床研究 010-59431886
CJCM 中医临床研究 2013 年第 5 卷第 14 期-1-
茵栀黄口服液对湿热郁蒸证型胎黄治疗效果的观察
Effect observation on treating NJ of Shire Yuzheng style with
Yinzhihuang oral liquid
刘改霞
(方城县中医院,河南方城,473200)
中图分类号: 文献标识码:A 文章编号:1674-7860(2013)14-0001-03
【摘要】目的:分析茵栀黄口服液对湿热郁蒸型胎黄的临床效果及安全性评估。方法:回顾性分析 2010 年 2 月~2012 年
8 月在我科住院治疗的患儿的临床资料,从中选取符合诊断标准的病例 90 例,其中单纯光疗组 30 例(A 组)使用蓝光毯治疗,
苯巴比妥联合光疗组 30 例(B 组),茵栀黄口服液联合光疗组 30 例(C 组),疗程为 5d。治疗结束后观察三组患者治疗前后血清
胆红素浓度的变化,并做出疗效判断。结果:治疗 5d 后三组总有效率两两比较,苯巴比妥联合光疗组和茵栀黄口服液联合光疗组
与单纯光疗组比较差异均有统计学意义(P<),苯巴比妥联合光疗组与茵栀黄口服液联合光疗组比较差异无统计学意义
(P>)。三种方案治疗第 3d 及第 5d 较治疗前血清胆红素浓度均降低(均 P<);治疗后三组患儿血清胆红素浓度比较经方
差分析差异有统计学意义(P<)。茵栀黄口服液联合光疗组大便次数高于其他两组,经 t 检验差异均有统计学意义(P<),
茵栀黄口服液联合光疗组有 %的患儿每天大便次数超过 5 次,该比例显著高于其他两组;茵栀黄口服液联合光疗组皮疹的发
生率高于苯巴比妥联合光疗组(P<),但是和单纯光疗组没有显著差异(P>)。结论:茵栀黄口服液联合蓝光治疗新生儿
湿热郁蒸型胎黄具有较好的疗效和安全性。
【关键词】茵栀黄口服液;湿热郁蒸证;胎黄
【Abstract】 Objective: To analyze the clinical effect of Yinzhihuang oral liquid on treating NJ ( neonatal jaundice) of Shire Yuzheng
style. Methods: 90 cases were equally divided into three groups. Phototherapy alone group (group A) was given blue blanket. Phenobarbital
combined with phototherapy group (group B) and Yinzhihuang oral bined with phototherapy group (group C). 5 days for a
course. To observe the changes in serum bilirubin concentration before and after treatment of the three groups. Results: The differences
between B and A, C and A were statistically significant (P<). The differences between B and C were not statistically significant
(P>). The serum bilirubin concentrations after 3-day and 5-day treatment all dropped (P<). Defecate frequency of the group C was
the highest and the differences were statistically significant (P<). % of the group C defecate over 5 times, higher than the other two
groups. The incidence of rash of the group C was higher than group B (P<). But there was no difference with the group A (P>).
Conclusion: Yin