文档介绍：62例不稳定型心绞痛患者窦性心率震荡临床研究
(作者:___________单位: ___________邮编: ___________)
作者:王锋刘杰闫兴国吴秀明罗群吴玉超
【摘要】目的观察不稳定型心绞痛(unstable angina pectoris, UAP)患者窦性心率震荡(heart rate turbulence, HRT)现象的特征并探讨其临床意义。方法选择62例UAP患者和在性别、年龄上相匹配的60例健康者分别作为UAP组和对照组,UAP组内分为高危组(n=20)、中危组(n=22)、低危组(n=20);均接受24 h Holter检查,定量测量HRT包括震荡初始(TO)和震荡斜率(TS)2个指标,并进行统计学处理。结果 UAP组TO明显高于对照组〔(±)%vs.(-±)%,P<〕,TS明显低于对照组〔(±) ms/RRI vs.(±) ms/RRI,P<〕;UAP组中低危组TO明显低于高危组〔(-±)%vs. (±)%,P<〕,低危组TS明显高于高危组〔(±) ms/RRI vs.(±) ms/RRI,P<〕;中危组与高危组及低危组与中危组比较均无明显差异。结论 UAP患者中HRT现象明显减弱,在高危组和低危组之间差异有显著性,可以作为预测UAP预后和高危患者的新指标。
【关键词】窦性心率震荡;心绞痛,不稳定型;动态心电图;危险性评估;自主神经功能;预后
Abstract: Objective To explore the features o
f heart rate turbulence (HRT) in patients with unstable angina pectoris (UAP) and its clinical significance. Methods Sixty-two patients with UAP and sixty healthy controls were enrolled in the study. The UAP patient group was subdivided into high- middle- and low-risk groups (n=20, 22 and 20 repectively). The HRT, including its turbulence onset (TO) and turbulence slope (TS) were determined by using digitized Holter recordings. pared to that in control group, TO was significantly higher in UAP group[(±0. 33)% vs. (-±)%, P<]; TS was significantly lower in UAP group [(±) ms/RRI vs. (±) ms/RRI, P<]. Compared to that in high