文档介绍：2005~2008年肺炎克雷伯菌的耐药性分析
(作者:___________单位: ___________邮编: ___________)
【摘要】目的监测肺炎克雷伯菌(Kpn)超广谱β-内酰胺酶(ESBLs)的产生及其对常用抗生素的耐药性。方法对浙江大学医学院附属妇产科医院2005年1月~2008年6月分离所得392株克雷伯菌,采用标准纸片扩散确证法检测其ESBLs产生率,采用K-B法进行药敏监测。%%。亚胺培南仍是对肺炎克雷伯最有效的抗菌药物,未出现耐药株;哌拉西林/他唑巴坦也有较好的抑菌活性。结论本院肺炎克雷伯菌产ESBLs率较高;亚胺培南仍然为最有效的抗生素;应采取措施控制产ESBLs肺炎克雷伯菌感染。
【关键词】克雷伯菌,肺炎;超广谱β-内酰胺酶;耐药性;抗菌药物
[Abstract] Objective To determine the antibiotic resistance and the productive rate of extended-spectrum β-lactamase(ESBLs) of Klebsiella pneumoniae(Kpn).Methods 392 strains of Klebsiella pneumoniae were isolated from Woman
’s Hospital affiliated to Medicine School of Zhejiang University during 2005 to June 2008,then antibiotic susceptibility test was peformed by Kirby-Bauer disk diffusion production was performed by the standard disk diffusion ESBLs productive rate was from % up to % on Klebsiella remained a strong antimicrobial activity and there wasn’t resistant strain to -tazobactam had same antimicrobial activity to ESBLs production of Klebsiella pneumoniae has significantly producing strains are most senstive to should be taken to control the infection of ESBLs producing strains.
[Key words] Klebsiella pneumoniae;extended-spectrum β-lactamase;drug resistance;antibacterials
肺炎克雷伯菌