文档介绍：Alport综合征眼部临床表现分析
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作者:徐建敏,张士胜,张琼,周颖明,朱彩红,葛健,王玲
【摘要】目的:总结Alport综合征的临床表现,尤其是眼部特征。方法:回顾性分析32例被确诊为Alport综合征患者的内科、耳鼻喉科和眼科检查结果。结果:患者30例(%)有疾病家族史。所有患者均有不同程度的肾脏病变:18例(%)有肾功能衰竭,4例(%)肾功能不全,10例(%)血尿。患者20例(%)有感音神经性耳聋。患者13例(%)有眼部异常表现,其中5例(%)为典型性改变:前圆锥晶体3例,黄斑周围斑点2例。结论:眼部异常不是Alport综合征诊断的必需条件,但因其典型的眼科表现应当引起眼科医师的注意,以便早期诊断治疗。
【关键词】 Alport综合征;前圆锥晶状体;黄斑斑点
Abstract A 20yearold healthy lady was admitted for septic arthritis in the right knee. Two weeks after the onset of joint pain, plained progressive blurring of vision in both eyes. Slitlamp examination revealed evidence of inflammation in both anterior and posterior segments. There were multiple chorioretinal lesions on
both fundi. Synovial fluid aspiration of the right knee and blood culture grew us aureus. She responded well to topical and systemic antibiotics. Her final visual acuity was 6/6 in both eyes. This case illustrates a rare presentation of bilateral endogenous endophthalmitis in an petent young patient presenting with a concurrent septic arthritis. Early diagnosis and a prompt management carry a favorable visual prognosis.
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KEYWORDS: septic arthritis; endogenous endophthalmitis; petent
INTRODUCTION
Endogenous endophthalmitis is relatively a rare condition but carries severe and potentially blinding ocular infection. It is caused by a varie