文档介绍：CT检查对于系统性红斑狼疮脑病的诊断价值
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作者:贾玉昌武东杰李师佳姚鹏鹏张霞丁云云李季一
【摘要】目的观察系统性红斑狼疮性脑病(SLEE) 在CT检查时的影像学表现。方法回顾性分析9例经临床诊断符合系统性红斑狼疮脑病患者的资料,所用病人均行CT检查,并分析其CT 表现。结果主要CT 表现:(1)弥漫性低密度灶(3 例),部位不定,单发或多发,形态不规则,边界模糊,占位效应较轻;(2)局限性低密度灶(4例),主要位于基底节区及脑干;(3)轻度脑萎缩(2例),均呈弥漫性。结论 CT可以对系统性红斑狼疮脑病的早期发现、鉴别诊断及疗效评价提供参考,但对系统性红斑狼疮脑病的诊断,需结合临床资料。
【关键词】系统性红斑狼疮;脑病;CT
【Abstract】 Objective To study the CT finding of systemic lupus erythematosus encephalopathy (SLEE).Methods The CT findings of 9 cases with SLEE proved by clinical data were retrospectively analyzed. Results The main CT findings of SLEE were that as follows:Diffused hypodense cerebral parenchyma (3 cases) characterized by indefinite position,single or multiple foci,irregular shape, indistinct border, and mild mass effect;Focal hypodense cerebral parenchyma (4 cases), mostly in the region of basal ganglion and brain stem;Mild brain atrophy (2 casses) which was local or diffuse. Conclusion Early diagnosis of SLEE, valuable references on differential diagnosis and evaluation of posttherapeutic effect might be provided by CT, however, definite diagnosis of SLEE should be made bination with the clinical characteristics of the disease.
【Key words】 Systemic lupus erythematsus;Encephalopathy; CT
系统性红斑狼疮(SLE) 是一种常见自身免疫性疾病,常伴多脏器损害,其中脑部损害为常见严重并发症。系统性红斑狼疮脑病(SLEE) 是SLE 死亡的主要原因之一[1] 。50%~75%的SLE 患者合并中枢神经系统受累,特别是导致脑部损害[2]。作者收