文档介绍：“双固一通”针法对糖尿病大鼠血清IL-6的影响
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【摘要】目的观测“双固一通”针刺法对糖尿病大鼠血清IL-6的影响。方法 180~220 g Wistar大鼠73只,13只为正常对照(A组),另60只行链脲左菌素腹腔注射造模,造模成功的大鼠随机分为模型组(B组)、“一通”治疗组(C组)、“双固一通”针刺治疗组(D组)和常规针刺治疗组(E组)。治疗2个疗程后运用放射免疫分析法检测各组血清白细胞介素-6(IL-6),运用血糖仪检测各组血糖。结果 C组糖尿病大鼠血糖水平有降低趋势,IL-6水平下降,但与模型组比较,差异无显著性意义()。D组和E组均明显降低糖尿病大鼠的血糖水平(),使糖尿病大鼠升高的血清IL-6水平降低(),在降低IL-6水平方面,D组效果更好()。结论“双固一通”针法使糖尿病大鼠升高的炎症细胞因子IL-6降低,这可能是其抑制糖尿病炎症反应、改善胰岛素抵抗、保护胰岛β细胞的功能并防治糖尿病血管并发症的重要机制之一。
【关键词】实验性糖尿病;“双固一通”针法;白细胞介素-6;胰岛素抵抗
Abstract:Objective To investigate the effect of
“Shuangguyitong acupuncture therapy on serum interleukin-6 of streptozotocin (STZ) induced diabetic rats. Methods Among seventy-three 180~220 g Wistar rats, thirteen were assigned as normal control group (group A) and sixty were induced diabetes by injecting STZ into celiac cavity. The diabetic rats were randomly divided into model group(group B), “Yitong” treatment group (group C), “Shuangguyitong” acupuncture group (group D) mon acupuncture group (group E). After two courses of treatment, serum IL-6 was tested by radioimmunoassay (RIA) . The blood glucose was measured by sugar equipment. Results The high blood glucose of the diabetic rats were lowered significantly in group D and E (). Group D had better effect on lowering IL-6 than group E (). Conclusion “Shuangguyitong” acupuncture therapy reduces t