文档介绍：不同孕期乙型肝炎病毒宫内感染率差别的荟萃分析
作者:闫永平李端徐德忠陈长生王雪萍
【关键词】宫内传播
关键词: 肝炎,乙型;宫内传播;感染率;Meta分析
摘要:目的分析不同孕期乙型肝炎病毒宫内感染率的差异,探索HBV宫内感染发生的时间. 方法运用Meta分析技术对9个不同孕期HBV母胎传播发生率研究进行定量综合分析. 结果孕早期的宫内感染率最低(%),而孕晚期的感染率(%)高于孕中期(%)(d=,%CI=-).对各研究结果做齐性检验,未见显著差异(P&gt;). 结论 HBV宫内感染可发生在孕期的各个阶段,但主要的发生时间是孕晚期.

Keywords:hepatitis B;intrauterine transmission;infection rate;Meta-analysis

Abstract:AIM To analyze the difference of intrauterine in-fection rate in different periods of pregnancy and to determine the timing of HBV intrauterine Meta-analysis was used to evaluate the data extracted from9pub-lished papers which were about the infection rate among dif-ferent p
eriods in HBV intrauterine In-trauterine infection rate at early gestation was the lowest(%),and infection rate at late gestation(%)was higher than that of middle gestation(%)(d=,%CI=-).Homogeneity test results dis-played no significant The in-trauterine infection may occur during various periods of preg-nancy,but the main timing is possibly at the late gestation.

0 引言

乙型肝炎病毒(HBV)[1-3] .我们对国内以HBsAg阳性孕妇的引产或流产胎儿为研究对象的9篇文献,用Meta分析的方法将这些研究结果进行综合分析,以便更准确的探索HBV宫内感染发生的时间.

1 材料和方法

材料通过《中文科技资料目录》,文献追溯和人工查阅文献方法,、方法及判定结果,因此分