文档介绍：老年黄斑变性43例光学相干断层扫描分析
【摘要】目的:研究老年黄斑变性的光学相干断层扫描(optical coherence tomography,OCT)特征。方法:对经眼底荧光造影(fundus fluorescein angiography,FFA)确诊的老年黄斑变性患者43例45眼,其中湿性型28例30眼、干性型15例15眼,按年龄匹配的正常人30例43眼利用OCT分别进行检测。观察黄斑部神经纤维层(nerve fiber layer of macular,MNFL)、色素上皮/脉络膜毛细血管复合层(retinal pigment epithelium/ choriocapillaris, )及视网膜神经上皮层(retinal neurepithelium layer,RNE)的厚度变化。应用秩和检验比较其差异性。结果:MNFL厚度:±、±、±,湿性型组与其他组比较差异有显著性(P﹤)。RNE厚度:±、±、±,湿性型组与其他组比较差异有显著性(P﹤)。厚度:±、±、±,湿性型组与其他组比较差异有显著性(P﹤)。结论:黄斑部神经纤维层厚度、视网膜神经上皮层厚度及色素上皮/脉络膜毛细血管复合层厚度随着老年黄斑变性病程的发展,其厚度增加。OCT可以作为湿性型老年黄斑变性发生与发展的监测工具之一。
【关键词】光学相干断层扫描老年黄斑变性
Optical coherence tomography on age-related macular degeneration
Abstract AIM: To observe the features of age-related macular degeneration (ARMD) on the optical coherence tomography (OCT). METHODS: OCT was used to measure the healthy volunteers (30 people, 43 normal eyes) and patients with age-related macular degeneration (43 people, 45 eyes) that were divided into wet type group (28 person 30 eyes) and dry type group (15 person 15 eyes) were diagnosed by fundus fluorescein angiography (FFA). The differences among the normal group and the age-related macular degeneration groups pared. Statistical analysis was perfo