文档介绍：脉管肿瘤与脉管畸形的临床特点及治疗
潘凌霄叶财盛郑文博黄勇波叶润仪李松奇李晓曦王深明
【摘要】【目的】总结脉管性疾病(脉管肿瘤与脉管畸形)住院患者的临床资料,探讨该疾病的临床特点以及治疗方式?【方法】对中山大学附属第一医院2006年1月至2009年9月期间的592例脉管肿瘤及脉管畸形住院患者的临床资料进行回顾性分析?【结果】脉管肿瘤187例(%),脉管畸形405例(%)?脉管肿瘤及脉管畸形最常见的受累部位分别为头颈部(%)及下肢(%);前者出现临床不适症状的比例(%)低于后者(%);前者病灶累及肌肉或骨关节的比例(%)低于后者(%),差异有统计学意义(P < );两组在治疗方式的选择上不尽相同,差异有统计学意义(P < )?【结论】脉管肿瘤与脉管畸形患者的临床特点各异,应个体化选择治疗方案?
【关键词】脉管肿瘤;脉管畸形;临床特点;治疗
Abstract: 【Objective】 This hospital based retrospective study assessed some clinical characteristics and therapies for patients with vascular anomalies (vascular tumors or vascular malformations) in southeast China. 【Methods】A total of 592 vascular anomalies patients, admitted to the First Affiliated Hospital of Sun Yat-sen University from January 2006 to September 2009, were enrolled in the study. Data for clinical characteristics and therapies were collected and analyzed. 【Results】 Of the 592 cases, vascular tumors and vascular malformations accounted for % an
d %, respectively. The monly involved areas of vascular tumors and vascular malformations were head and neck (%) and lower limbs (%), separately. % of patients with vascular tumors had definite symptoms, comparing % of patients did in vascular malformations group. % of lesions involved muscle, bone or joint in vascular tumors, which was significantly lower than that (%) in vascular malformations (P<). What's more, there were different choices for therapies in these two groups. 【Conclusions】 Due to the clinical heterogeneity in vascular tumors and vascular malformations, therapies should be undertaken individually.
Key words: vascular tumors; vascular malformations; clinical characteristics; therapy
鼻咽癌是中国广东等地的高发恶性肿瘤,发病率居头颈部恶性肿瘤的首位,好发于鼻咽部的咽隐窝及顶后壁,与咽鼓管咽口比邻,其主要治疗手段是高剂量放射治疗,为达到局部根治及控制淋巴结转移,放射野通常包括从颅底至颈根部?中耳腔?乳突和咽鼓管等结构处于放射野的中心位置不可避免的遭受放射损伤,可出现一系列早期并发症,比如咽鼓管损伤?中耳黏膜损伤?分泌性中耳炎等,随着放射剂量的增加损伤逐渐加重,而且许多损伤是不可逆的[1]?耳部最常见的并发症是分泌性中耳炎及内耳毛细胞放射性损伤导致听力下降?对于分泌性中耳炎治疗