文档介绍：布-加综合征患者血清甲胎蛋白水平的检测及其临床意义
作者:邹文卫祖茂衡黄光明
【摘要】目的探讨布-加综合征(BCS)患者血清甲胎蛋白(AFP)的水平及其临床意义。方法回顾性分析169例BCS患者的平均血清AFP水平。结果①160例单纯性BCS患者的AFP水平为(±)μg/L (95%参考值范围:0~ μg/L),位于正常人群总体AFP水平区间(0~20 μg/L)内。②9例BCS合并肝癌患者AFP水平:2例>1000 μg/L,5例为20~400 μg/L,2例<20 μg/L。结论①单纯BCS患者平均血清AFP水平在正常范围;②合并肝癌的BCS患者血清AFP水平明显高于单纯性BCS患者。
【关键词】布-加综合征;甲胎蛋白;肝癌
Abstract: Objective To investigate the level of serum AFP in patients with Budd-Chiari syndrome (BCS) and its clinical significance. Methods A retrospective analysis of serum AFP level was carried out in 169 patients with BCS who received interventional therapy. Results (1) The average serum AFP level of 160 patients with simple BCS was (±) μg/L (95% reference value range: 0- μg/L), which were located in the siding-to-siding block inner (0-20 μg/L). (2) In the 9 BCS patients together with hepatocarcinoma, the serum AFP level was over 1000 μg/L in 2 cases, ranged from 20 to 400
μg/L in 5 cases, and was below 20 μg/L in 2 cases. Conclusion (1) The average serum AFP level in simple BCS patients is within the normal range. (2) The serum AFP level in BCS patients with liver cancer is obviously higher than that of simple BCS patients.
Key words: Budd-Chiari syndrome; alpha-fetoprotein (AFP); hepatocarcinoma
布-加综合征(Budd-Chiari syndrome, BCS)是由于肝静脉或(和)下腔静脉阻塞导致肝静脉或(和)下腔静脉血液回流障碍而产生的门静脉高压或(和)下腔静脉高压的一系列症候群[1]。由于肝脏血液流出道阻塞,肝脏长期处于淤血状态,可导致肝