文档介绍：纳络酮联合氨茶碱治疗早产儿原发性呼吸暂停疗效观察
作者:余连芝连文喜钟秋红
【摘要】目的探讨纳络酮联合氨茶碱治疗早产儿原发性呼吸暂停的疗效。方法将60例原发性呼吸暂停的早产儿分为治疗组(加用纳络酮辅助组)30例和对照组(常规应用氨茶碱组)30例, 观察两组病例接受治疗后呼吸暂停消失时间、氨茶碱维持时间及总有效率。结果两组病例接受治疗后在呼吸暂停消失时间、氨茶碱维持时间等方面治疗组优于对照组(P<), 总有效率治疗组也优于对照组(P<)。结论纳络酮辅助氨茶碱治疗早产儿原发性呼吸暂停可缩短症状消失时间、减少氨茶碱使用时间并提高总有效率。
【关键词】纳络酮氨茶碱呼吸暂停早产儿
【Abstract】Objective:To investigate the clinical effects of Naloxone plus Aminophylline in the treatment of premature infants with :60 newborns were randomly divided into treatment group (30 cases; additionally used Naloxone) and control group (30 cases; routine used Aminophylline) . After the treatment, statistically analyzed the following data: the time from the treatment beginning until the apnea disappeared, the holdup time of Aminophylline, and the total effective rate. Results
:There were significant differences between the two groups in the time of treatment beginning until the apnea disappeared, and in the holdup time of Aminophylline (P <). Also,there were significant differences between the two groups in the total effective rate (P<). Conclusion:Naloxone could speed the symptom disappearance, shorten the time of using aminophylline and raise the total effective rate.
【Key words】Naloxone Aminophylline premature infant apnea
新生儿呼吸暂停是指呼吸暂停时间≥15~20s,常伴有心率减慢<100次/min,或出现紫绀、肌张力低下。呼吸暂停是早产儿常见症状之一,%~%,%,超低出生体重儿可