文档介绍：:..泰勒宁胶囊治疗中晚期癌痛的临床疗效观察【摘要】目的探讨泰勒宁胶囊在中晩期肿瘤患者疼痛治疗中的临床疗效。方法实验组及对照组各42例中晚期癌症疼痛患者口服泰勒宁胶囊及曲马朵胶囊,观察疼痛缓解程度及毒副作用。结果实验组与对照组比较,平均疼痛强度差、中度以上疼痛缓解率及重度疼痛患者完全疼痛缓解率,两组间无明显差异(P均〉),但对于屮度疼痛患者,泰勒宁的完全缓解率明显高于曲马朵(P<)o结论泰勒宁胶囊治疗中晚期癌症疼痛疗效确切,•且副作用小,适用于癌痛“三阶梯治疗”的第二,三阶段,尤其是第二阶梯治疗阶段。【关键词】泰勒宁;癌症;eofTyloxforCancerPainatMiddleandAdvaneedStageWanYoufeng,WuXiaoan(DepartmentofCarcinoma,PLA174thHospital,Xiamen361003,China)Abstract:eoftyloxcapsuleforthepaincausedbymiddleandadvaneedcancer・MethodsPatientsweredividedintoexperimentalgroupandcontrolgroup(42patientspergroup),,therewerenosignificantdifferencesbetweenthetwogroupsinmeanpainintensitydifference,moderateorclearpainalleviationrate,pletepainalleviationrateinthepatientswithseverepain(P&gt;).However,inthepatientswithmediumpain,pletealleviationratewasfoundinthosetreatedwithty1ox(P&It;).ConclusionTyloxcapsule,whichleadstoslightadverseeffect,isdefinitelyeffectiveonthepaincausedbymiddleandadvaneedcancer,andfitforthree-gradetherapyofcancerpain,:tylox;carcinoma;pain临床治疗癌症疼痛一般都遵循三阶梯止痛指导原则,口服镇痛药物仍然是目前处理屮晚期癌症疼痛主要方法和有效手段之一。poundcapsuleofoxycodoneandacetaminophen,USR,商品名:Tylox)为疑考酮与对乙酰氨基酚复方麻醉性镇痛药。轻考酮为阿片受体强激动剂,自1917年首次应用于临床,并可与对乙酰氨基酚、阿司匹林等联合用药[1],其在许多国家得到广泛