文档介绍：精神疾病患者血清睾***和雌二醇水平研究        【摘要】目的:了解首发精神分裂症和情感性精神障碍患者血清睾***和雌二醇的变化。方法:以放射免疫法对首次发病的54例精神分裂症患者和37例情感性精神障碍患者血清中睾***和雌二醇进行测定,并与正常健康者作对照。结果:男性精神分裂症患者血清雌二醇浓度显著高于对照组男性,女性情感性精神障碍患者血清睾***浓度显著高于对照组和精神分裂症组女性。治疗后女性患者血清雌二醇浓度显著下降,对睾***浓度影响不大。结论:精神分裂症和情感性精神障碍患者发病早期性激素的分泌尚处于相对稳定状态。精神药物可导致性激素水平不同程度的变化。【关键词】精神分裂症情感性精神障碍睾***雌二醇Astudyonserumtestosteroneandestradiollevelsinpatientswithfirst-onsetschizophreniaoraffectivedisorderLiPeiying(JiningMentalHospital,Shandong272051) 【Abstract】 Objective:Toobservethechangeofserumtestosterone(T)andestradiol(E2)levelsbeforeandaftertreatmentwithpsychotropicdrugsinpatientswithfirst-onsetschizophreniaoraffectivedisorder. Method:SerumTandE2weremeasuredwithradioimmuneassayin54first-. Results:TheserumE2levelwassignificantlyhigherinmalefirst-onsetschizophrenicpatientsthaninmalecontrols,. Conclusion:. 【Keywords】Schizophrenia Affectivedisorder Testosterone Estradiol