文档介绍:
高碘摄入和自身免疫性甲状腺疾病的相关
性研究#
孙明玉1,陈迪群1,李明1,李强2,赵淑华3,刘守军1,孙殿军4**
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(1. 哈尔滨医科大学中国疾病预防控制中心地方病控制中心碘缺乏病防治研究所,哈尔滨
150081;
2. 哈尔滨医科大学附属第二医院内分泌科,哈尔滨 150081;
3. 哈尔滨医科大学保健室,哈尔滨 150081;
4. 哈尔滨医科大学中国疾病预防控制中心地方病控制中心,哈尔滨 150081)
摘要:目的探讨高碘摄入和自身免疫性甲状腺疾病的相关性。方法通过尿中碘的砷铈催化
分光光度测定方法检测 106 例 GD 患者、44 例 HT 患者和 233 例健康对照人群的碘摄入量水
平。结果与健康对照人群相比,GD 患者尿碘水平显著增高,并与病程相关;尿碘水平≥
300µg/L 和在 100-199µg/L 时分别是 GD 的危险因素和保护因素。HT 患者的尿碘水平和健康
对照人群无显著差异,与临床指征并无相关性。结论高碘摄入可能与 GD 发生相关,而与
HT 发生无关,有待进一步扩大样本进行研究。
关键词:地方病学;AITD;高碘;Graves;HT
中图分类号:R581
Study on correlation between excess iodine intake and
AITDs
SUN Mingyu1, CHEN Diqun1, LI Ming1, LI Qiang2, ZHAO Shuhua3, LIU Shoujun1,
SUN Dianjun4
(1. Institute of Iodine Deficiency Disorders,Center for Endemic Disease Control,Chinese Center
for Disease Control and Prevention,Harbin Medical University,Harbin 150081;
2. Department of Endocrine and Metabolic Diseases,The Second Affiliated Hospital of Harbin
Medical University,Harbin 150081;
3. Health Care Room,Harbin Medical University,Harbin 150081;
4. Center for Endemic Disease Control,Chinese Center for Disease Control and Prevention,Harbin
Medical University,Harbin 150081)
Abstract: Objective: Study on correlation between excess iodine intake and AITDs. Methods: The
urine iodine level of 106 GD,44HTand 233 healthy controls were measured by As3+Ce4+catalytic
spectrophotometry