生脉散治疗心血管疾病的实验研究进展1.doc

文档介绍：
生脉散治疗心血管疾病的实验研究进展#
李晓佳1,王瑜1,陈莉莉1,王小莹2**
(1. 天津中医药大学中医药研究院,天津 300193;
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2. 天津中医药大学中药学院,天津 300193)
摘要:生脉散最早见于金代张元素《医学启源》,由人参,麦门冬,五味子组成,具有益气
生津,敛阴止汗的功能,为临床益气养阴的常用方。近年来国内外学者对生脉散及其组成药
物进行了深层次药理学研究,利用整体、离体、细胞等模型,研究其作用的科学内涵。笔者
查阅了 2003-2013 年有关生脉散及其加减方应用于心血管疾病的药理实验研究相关文献,以
期为临床用药提供指导。
关键词:生脉散;抗氧化;抗炎;内皮保护;改善血流动力学
中图分类号:
Research development of the experiments on Shengmai San
in treating cardiovascular diseases
LI Xiaojia1, WANG Yu2, CHEN Lili2, WANG Xiaoying2
(1. Tianjin University of Traditional Chinese Medicine, Tianjin 300193;
2. Tianjin University of Traditional Chinese Medicine,Tianjin 300193)
Abstract: Shengmai San was first recored in "Yixue Qiyuan" by Zhang Yuansu in Jin Dinasty. It
is constituted by Radix ginseng, Radix Ophiopogonis and Fructus schisandrae. The formula is
administered to patients who have suffered a serious illness, especially heart attack, or severe
bronchitis. In recent years, many scholars have researched the mechnisms of Shengmai San and its
components both in vivo and in vitro. The aim of this manuscript is to review the articles about the
experiments of Shengmai San which were published in the last 10 years (2003-2013), in order to
provide guidance for clinic use.
Key words: Shengmai San; Antioxidant; Anti-inflammatory; Protection of endothelium; Improve
hemodynamics
0 引言
生脉散最早见于金代张元素《医学启源》“麦门冬