文档介绍:MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, Mar. 2002, p. 39–63 Vol. 66, No. 1
1092-2172/02/$ DOI: .–
Copyright © 2002, American Society for Microbiology. All Rights Reserved.
Molecular Biologist’s Guide to Proteomics
Paul R. Graves1 and Timothy A. J. Haystead1,2*
Department of Pharmacology and Cancer Biology, Duke University,1 and Serenex Inc.,2 Durham, North Carolina 27710
INTRODUCTION .........................................................................................................................................................40
Definitions..................................................................................................................................................................40
Proteomics Origins ...................................................................................................................................................40
Genome Information ................................................................................................................................................41
Why Proteomics?.......................................................................................................................................................41
Annotation of the genome....................................................................................................................................41
Protein expression studies...................................................................................................................................41
Protein function ....................................................................................................................................................42
Protein modifications ...........................................................................................................................................42
Protein localization partmentalization ........................