文档介绍：1
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耳鼻咽喉头颈外科学
第二篇
鼻科学及颅面疾病（3）
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第十一章 鼻黏膜高反应性鼻病
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第一节 变态反应性鼻炎
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Respiratory mucosa in nose
The nasal mucosa showed by transmi-
ssional electromi-Croscope.
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The picture of normal mucosa
showed by nasal endoscope
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Nasal hyper-reactivity
Nasal cavity :
First line of airway
Sensitivity:
rich nerve distribution
Mucosal compound:
respiratory epithelial cells Goblet cell glands (serous or mucous) rich vessels
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Immune compound:
Toll-like receptors lymphocytes (T, B) serous cells mast cells epithelial cells
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Response of nose induced by some factors
Challenge factors:
enviromental
Weather、temperature、humidity
inhalants:
Dust、allergen、chemicals pollution
most of above
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Intrinsic:
nervous、stress or disappoint、depress or anxious
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