文档介绍：中药药理与中药现代化暨钙研讨会论文汇编·245· 脑必通对血小板聚集功能的影响高健洪(苏州大学医学院药理教研室· 摘要目的观察脑必通胶囊对大鼠血小板聚集功能的影响。方法给大鼠分别灌服脑必通胶囊350、175、 mg· kg“10天后,观察药物对ADP诱导的血小板聚集作用,实验以阿司匹林为阳性对照药。结果脑必通胶囊350、175 mg ·kg。在体内可以抑制连续给药10天大鼠血小板对ADP诱烨顾振纶苏州中药研究所,苏州 215007) 导的血小板聚集,%%(P<)。 mg·kg_1对ADP诱导的血小板聚集无明显抑制作用。结论脑必通胶囊对血小板聚集功能有明显的抑制作用。关键词啦小板;脑必通;腺苷二磷酸;大鼠 Effects of Braintone on Platelet Aggregation Function GAO Jian。HONG Ye。GU Zhen-Lun (Dept ofPharmacology,Medical College of Soochow Universiy;Suzhou Institute of Chinese MateriaMedica,Suzhou 215007) ABSTRACT AIM To study the effectofBraintone capsule on rats platelet After treated orally for10days with Braintone capsule(350、175、 mg·kg_1) rat,platelet aggregation induced by ADP was observed. The control group was given The study showed that Braintone capsule(350、175 mg·kg_1)can in- hibit rat platelet aggregation induced by ADP and theplatelet aggregation rates were %and %(P<),How- ever,Braintone capsule mg·kg—was - SION These results suggested that Braintone capsule(350、 175 mg·kg一1)were more powerful inhibitors ofplatelet gregation KEY WORDS platelet aggregation;P Braintone;ADP;rat NBT胶囊对大鼠急性血瘀模型血液流变学的影响洪烨高健(苏州大学医学院药理教研室· 摘要目的观察NBT胶囊对大鼠急性血瘀模型血液流变学的影响。方法给大鼠分别灌服NBT胶囊350、175、 mg·kg-1 10d后,腹腔注射。肾上腺素加冰水浴造成大鼠急性血瘀模型,实验以银杏叶片为对照药物,观测NBT胶囊对血瘀模型大鼠血液流变学各项指标(全血粘度、全血还原粘度、血浆粘度,红细胞压积、纤维蛋白原,红细胞聚集指