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文档介绍:Copyright 2013 American Medical Association. All rights reserved. 2014 Evidence-Based Guideline for the Management of High Blood Pressure inAdults Report Fromthe Panel Members Appointed to the Eighth Joint mittee (JNC 8) Paul A. James, MD; Suzanne Oparil, MD; Barry L. Carter, PharmD; William C. Cushman, MD; Cheryl Dennison-Himmelfarb, RN, ANP, PhD; Joel Handler, MD; Daniel T. Lackland, DrPH; Michael L. LeFevre, MD, MSPH; Thomas D. MacKenzie, MD, MSPH; Olugbenga Ogedegbe, MD, MPH, MS; Sidney C. Smith Jr, MD; Laura P. Svetkey, MD, MHS; Sandra J. Taler, MD; Raymond R. Townsend, MD; Jackson T. Wright Jr, MD, PhD; Andrew S. Narva, MD; Eduardo Ortiz, MD, MPH Hypertension is the moncondition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if not detected early and treated appropriately. Patients want to be assured that blood pressure (BP) treatment will reduce their disease burden, while clinicians want guidance on hypertension management using the best scientific evidence. This report takes a rigorous, evidence-based approach to mend treatment thresholds, goals, and medications in the management of hypertension in adults. Evidence was drawnfrom randomized controlled trials, which represent the gold standard for determining efficacy and effectiveness. Evidence quality and mendations were graded based on their effect on important es. There is strong evidence to support treating hypertensive persons aged 60years or older to a BP goal of less than 150/90mmHg and hypertensive persons 30through 59years of age to a diastolic goal of less than 90mmHg; however, there is insufficient evidence in hypertensive persons younger than 60years for a systolic goal, or in those younger than 30years for a diastolic goal, so the panel mends a BP of less than 140/90mmHg for those groups based on expert opinion. The same thresholds and goals are mended for hypertensive adults with diabetes or nondiabetic chronic kidney disease (CKD) as for the general h