文档介绍：EffectofYishenSanjielawonrenalInterstitialFibrosisandTGF-β1inRats ShiJianLiuJianhongChenXiaohongXingBing MaoJiarong ChineseMedicineHospitalofShaanxiProvince,Xian710003 Objective:ToobserveYishenSanjielawanditsagentsofRenalRehabilitationⅡcapsuleontheinhibitionofrenalinterstitialfibrosisin ratkidneytissueofrenalinterstitialfibrosisandtheimpactoftheexpressionfortransforminggrowthfactor-β1Methods:Theratmodelsofre :shamoperationgroup,modelgroup, ,/ Ⅱ changesofrenalinterstitialfibrosisusingHE,Massonstaining7daysafterformedicine,14days,21daysinratkidneymodelrespectively andtodeterminatetheexpressionsituationoftransforminggrowthfactor-β1inrenalinterstitialthroughthemethodofimmunohistochemistry. paredwiththesham-operatedgroup,themodelgroupandtheeachgroupofRenalRehabilitationⅡcapsuleshowedsignificant interstitialfibrosisofrenalpathologicalchanges(P<).EachgroupofRenalRehabilitationⅡcapsule(effectdose:~9g/kg) waslighterthanthemodelgroup,withsignificantdifference(P<).TheTGF-β1expressioninthemodelgroupandeachgroupofRenal RehabilitationⅡcapsulewassignificantlystrongerthant