文档介绍：Clinicopathological Significance of E-cadherin and PCNA Expression in
Hunman Non-small Cell Lung Cancer
Yi-fei ZHU, Shi-Ying ZHENG, Dong JIANG, Jun ZHAO
Department of Cardio-Thoracic Surgery, The First Affiliated Hospital of Suzhou University , Suzhou
215006, Jiangsu Province, China
Correspondence to: Dr. Shi-Ying Zheng, Department of Cardio-Thoracic Surgery, The First Affiliated
Hospital of Suzhou University ,Suzhou 215006, Jiangsu Province, China
Telephone: +86-512-65263570 Syzheng88@
immunohistochemistry
Abstract-This study was designed to assess
E-cadherin (E-cad)and proliferating cell nuclear I. Introduction
antigen (PCNA)expression as well as their Lung cancer is the leading cause of cancer
c1inicopatho1o ca1 significance in hunm an deaths in both women and men , and its
nonsmall cell lung cancers (NSCLCs).Possible incidence has increased markedlY in the past
molecular mechanisms of diferentiation and tumors,which present the
metastasis of NSCLCs are discussed. majority of 1ung tumors,are classifted primarily
Immuno-histochemical and imm unofluorescence into two subgroups : small cell lung cancer
double staining were performed to examine the (SCLC) and non-small cell 1ung cancer
expression of E-cad and PCNA in 68 primary (NSCLC).NSCLC posed of squamous
NSCLCs E-cad expression in squamous cell , adeno