文档介绍：中山大学生物化学课件
§ General features
Versatile in function
Being hard to study
Function via interaction
The interaction with other molecule (ligand) is reversible.
The interface between the binding site is complementary in structure, making such interaction highly specific.
Structure dynamicness of a protein is usually essential for such interactions.
liguofu
§ General features
§ Oxygen-binding proteins
§ Immunoglobulins
§ Muscle contraction
§4 Protein Function
liguofu
Quantitative description of interaction (1)
Protein + nLigand PLn
liguofu
Quantitative description of interaction (2)
If kd is constant
liguofu
Quantitative description of interaction (3)
If kd is not constant
Kd
liguofu
Quantitative description of interaction (4)
liguofu
Quantitative description of interaction (5)
liguofu
The iron-porphyrin in hemoglobin accounts for the red color of blood, the copper-porphyrin in hemocyanin for blue color of blood, and the magnesium-porphyrin in chlorophyll is responsible for the green of plants.
liguofu
Structure of Porphyrin
Pyrrole ring
Methene bridge
liguofu