文档介绍：Comprehensive Medicinal Chemistry II
Volume 2 : Strategy and Drug Research
Elsevier, 2006
Editors-in-Chief: John B. Taylor and David J. Triggle
ISBN: 0-08-044513-6
Introduction
The Intersection of Strategy and Drug Research, Pages 1-84, . Moos
An Academic Perspective, Pages 85-97, . Triggle
An Industry Perspective, Pages 99-135, W. Wierenga
Organizational Aspects and Strategies for Drug Discovery and Development
Project Management, Pages 137-158, Y. Nakagawa and L. Lehman
The Role of the Chemical Development, Quality, and Regulatory Affairs
Teams in Turning a Potent Agent into a Registered Product, Pages 159-172,
. Munk
Drug Development, Pages 173-202, P. Preziosi
In-House or Out-Source, Pages 203-223, . Connell
Pharma versus Biotech: Contracts, Collaborations, and Licensing, Pages
225-238, D. Cavalla
Managing Scientists, Leadership Strategies in Science, Pages 239-252,
. Sapienza
Innovation (Fighting against the Current), Pages 253-264, R. Root-Bernstein
Enabling Technologies in Drug Discovery: The Technical and Cultural
Integration of the New with the Old, Pages 265-287, M. Williams
How and Why to Apply the Latest Technology , Pages 289-557, .
Czarnik and H-Y Mei
How and When to Apply Absorption, Distribution, Metabolism, Excretion,
and Toxicity, Pages 559-572, . Zimmerman
Peptide and Protein Drugs: Issues and Solutions, Pages 573-601, .
Nestor
Peptidomimetic and Nonpeptide Drug Discovery: Receptor, Protease, and
Signal Transduction Therapeutic Targets, Pages 603-647, . Sawyer
Bioisosterism, Pages 649-711, . Wermuth, P. Ciapetti, B. Giethlen and P.
Bazzini
Chiral Drug Discovery and Development – From Concept Stage to Market
Launch, Pages 713-736, H.-J. Federsel
Promiscuous Ligands, Pages 737-752, . McGovern