文档介绍：2022 年 1 月中成药 January 2022
第 44 卷第 1 期 Fangfeng Tongsheng Pills ( Chuanxiong Ｒhizoma，Platycodonis Ｒadix，Glycyrrhizae Ｒadix et Ｒhizoma，
etc．) ． METHODS The analysis of 80% methanol extract of this drug was performed on a 25 ℃ thermostatic
Venusil MP C18 column ( 250 mm×4. 6 mm，5 μm) ，with the mobile phase comprising of acetonitrile-0. 1%acetic
acid flowing at 1. 0 mL /min in a gradient elution manner，the detection wavelength was set at 260 nm，the drift
tube temperature of ELSD was 90 ℃ ，the volumetric flow rate of atomizing airflow was 2. 5 mL /min，and the
atomizing temperature was 36 ℃ ．ＲESULTS Eight constituents showed good linear relationships within their own
ranges ( r ≥ 0. 999 5) ，whose average recoveries were 99. 35% － 99. 60% with the ＲSDs of 0. 52% － 1. 31%．
CONCLUSION This accurate，sensitive and reproducible method can be used for the quality control of Fangfeng
Tongsheng Pills．
KEY WOＲDS: Fangfeng Tongsheng Pills; chemical constituents; HPLC-UV-ELSD
收稿日期: 2021-06-07
基金项目: 国家自然科学基金资助项目 ( 81773892) ; 河南中医药大学科研苗圃工程项目 ( MP2020-68)
作者简介: 赵迪 ( 1986—) ，女，硕士，实验师，从事中药质量分析与新药研究。E-mail: zhaodiabcd@ sina．com
* 通信作者: 冯素香 ( 1971—) ，女，博士，教授，从事中药质量分析与新药研究。E-mail: fengsx221@ 163．com
382022 年 1 月中成药