文档介绍：该【胰腺疾病(英文)ppt 】是由【h377683120】上传分享，文档一共【48】页，该文档可以免费在线阅读，需要了解更多关于【胰腺疾病(英文)ppt 】的内容，可以使用淘豆网的站内搜索功能，选择自己适合的文档，以下文字是截取该文章内的部分文字，如需要获得完整电子版，请下载此文档到您的设备，方便您编辑和打印。胰腺疾病(英文)
解剖生理概要
解剖
头,颈,体,尾,钩突。
主胰管(ductofWirsung)
副胰管(ductofSantorini)
胰腺分泌
外分泌Exocrine
内分泌EndocrineB,A,D,D1,Gcell
c
Causes
Gallstones:60%(35–50%inUSA)
Alcohol:14%%(60%inUSA)
Duodenaljuicecountercurrentflow:SphincterofOddidysfunction
Trauma
Pancreascirculationdisorder
Otherfactors:
Drug:Azathioprine(硫唑嘌呤) 、6-Mercaptopurine(6-巯基嘌呤),
Pancreasdivisum(胰分裂),
Microlithiasis
Metaboliccause
Infectiouscauses,ascarisworms蛔虫,HIV-----
Miscellaneous
急性胰腺炎
Pathology
acuteedematouspancreatitis
acutehemorrhagicnecrotizingpancreatitis
(acutehemorrhagicpancreatitis,acutenecrotizingpancreatitis)
急性胰腺炎
Pathophysiology
Hypersecretionandobstruction
Self-enzymaticdigestion
EnhancementofVesselpermibilityCytokine,infection
Decreasedarterialperfusion
Edematoushemorrhagicnecrotizing
急性胰腺炎
Clinicalfinding
Abdominalpain
Abdominaldistention
Nauseaandvomiting
Peritonitis
Other:
Respiratoryfailure,confusion,ora、
Low-gradetomoderatefever
TachycardiaandhypotensionandShock
Mildjaundice,
Pleuraleffusion、
急性胰腺炎
急性胰腺炎
Peritonealirritationsign(Abdominaltenderness,reboundtendernessandrigidity)
Shiftingdullness
Decreasedbowelsounds
Cullen’sign:discolorationofperiumbilicalarea
GreyTurner’sign:discolorationofflanks
10
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Laboratoryfinding
Amylaseandlipase(elevationsofamylasearemoresensitivebutlessspecificthanlipaseinthediagnosisofacutepancreatitis)
500
400
300
200
100
0
01H24H48H5DAY
急性胰腺炎
Bloodamylase
Urineamylase
急性胰腺炎
Serumcalcium
Serumglucose
Bloodgasanalysis
Imunolipase
ALTandAST(gallstonepancreatitis)