文档介绍：接种水痘减毒活疫苗后发生水痘的临床特征分析
范篆玲
宁夏儿童福利院,宁夏银川 750001
[摘要] 目的探讨接种水痘减毒活疫苗对儿童的保护作用及意义。方法将同一流行期内的33例儿童水痘分为已接种水痘疫苗组和未接种水痘疫苗组,从临床特征、愈后情况进行对比分析。结果接种水痘疫苗组患儿较未接种水痘疫苗组临床症状轻,患儿体温基本均正常,水疱数目明显少,且合并上呼吸道感染症状明显减少,出疹及脱痂时间、病程和疗程明显缩短,差异有统计学意义(P<)。结论水痘减毒活疫苗具有免疫保护作用,儿童应及时接种,同时建议完善水痘免疫策略以提高其免疫持久性。
[ .jyqkous Region, 750001, China
[Abstract] Objective To study the protective effect and meaning of inoculating Live Attenuated Varicella ine on children. Methods 33 children suffered chickenpox in the same epidemic period ptoms and healing conditions of tptoms and healing conditions of the children ptoms of the children perature al, the number of blister uch less, the symptoms of upper respiratory tract infection significantly reduced, the breaking out in a rash and decrustation time and course of disease and course of treatment mune protective effect for children. Therefore, children should be inated prove chickenpox immunity strategy to enhance its immune persistence.
[Key ptoms
[简介] 范篆玲(—),女,宁夏人,本科,副主任医师,研究方向:儿科临床与儿童康复。
水痘(chi ckenpox,varicella)是由水痘-带状疱疹病毒(vari
cella-zostervirus)初次感染引起的急性传染病。主要发生在婴幼儿及学龄儿,以发热及成批出现周身性红色斑丘疹、疱疹、痂疹为特征[1],其传染力强,接触或飞沫均可传染,易感儿发病率可达95%以上。该病为自限性疾病,病后可获得终身免疫。以往因水痘症状轻,常不被人们重视,但也常有并发肺炎、脑炎甚至死亡的发生,据报道,我国儿童水痘的发病和危害日益凸显[2]。随着人们生活水平的提高,健康知识的增加及水痘减毒活疫苗的推广使用,许多照顾者及时给年满1岁的孩子接种水痘减毒活疫苗,以预防水痘的发生。但近年来在已接种水痘疫苗的人群中水痘流行却常有发生,然而据临床观察,接种水痘疫苗感染水痘的患儿症状较轻,病程短,临床表现很不典型。为探讨接种水痘减毒活疫苗对儿童的保护作用