文档介绍：EJCTS-5792; No of Pages 6
European Journal of Cardio-thoracic Surgery xxx (2007) xxx—xxx
ate/ejcts
Influence of a tilting prosthetic mitral valve orientation on the
left ventricular flow — an experimental in vivo ic
resonance imaging study
Heinrich Ma¨chler a,*, Gert Reiter b,e, Mathias Perthel c, Ulrike Reiter b,
Peter Bergmann a, Michael Zink d, Rainer Rienmu¨ller b, Joachim Laas c
a Division of Cardiac Surgery, Medical University Graz, A-8036 Graz, Austria
b Division of Radiology, Medical University Graz, Austria
c Division of Cardiac Surgery, Bad Bevensen, Germany
d Department of Anesthesiology, Medical University Graz, Austria
e Siemens Medical, Graz, Austria
Received 8 November 2006; received in revised form 10 February 2007; accepted 15 February 2007
Abstract
Objective: Orientation-related monoleaflet mechanical valve flow and velocity studies in the downstream are limited in mitral valve
replacement studies. Methods: In five sheep, ventricular blood flow was visualized prior to the implantation of a Medtronic Hall tilting valve
model. In six sheep, the implant orientation was either anatomical (disc aligned with the anterior leaflet) or anti-anatomical. The mitral
subvalvular apparatus was preserved. Sheep were positioned within an T field strength MR scanner (om Sonata; Siemens) to assess
time-dependent three dimensional blood flow. Results: