文档介绍：10/21/05 Gene Prediction (formerly Gene Prediction - 3)
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D Dobbs ISU - BCB 444/544X: Gene Prediction
Announcements
Exam 2 - next Friday
Posted online: Exam 2 Study Guide
544 Reading Assignment (2 papers)
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D Dobbs ISU - BCB 444/544X: Gene Prediction
Announcements
544 Semester Projects - Information needed:
Please send email to me (or David)
******@
Briefly describe:
Your background & current grad research
Is there a problem related to your research you would like to learn more about & develop as project for this course?
or
What would your ‘dream’ project be?
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D Dobbs ISU - BCB 444/544X: Gene Prediction
Announcements
2 Bioinformatics Seminars today (Fri Oct 21)
12:10 PM BCB Faculty Seminar in E164 Lagomarcino
“works”
Bob Jernigan, BBMB & Director,Baker Center for Bioinformatics & Biological Statistics
.edu/courses/BCB691-#Oct%2021
4:10 PM GDCB Special Seminar in 1414 MBB
“Integrating the Unknown-eome with Abiotic Stress works in Arabidopsis”
Ron Mittler, Dept. of Biochem & Mol Biology
University of Nevada, Reno
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D Dobbs ISU - BCB 444/544X: Gene Prediction
Gene Prediction & Regulation
Mon - Gene structure review:
Eukaryotes vs prokaryotes
Wed - Regulatory regions:
Promoters & enhancers
Fri - Predicting genes
- Predicting regulatory regions (?)
Next week: Predicting RNA structure (miRNAs, too)
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D Dobbs ISU - BCB 444/544X: Gene Prediction
Reading Assignment
Mount Bioinformatics
Chp 9 Gene Prediction & Regulation
pp 361-385 Predicting Promoters
Ck Errata: p/
* Brown Genomes 2 (NCBI textbooks online)
Sect 9 Overview: Assembly of Transcription plex
.gov/books/?rid=
Sect - DNA binding proteins, Transcription initiation
.gov/books/?rid=
* NOTE: Don’t worry about the details!!
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D Dobbs ISU - BCB 444/544X: Gene Prediction
Optional Reading
Reviews:
Zhang MQ (2002) Computational prediction of eukaryotic protein-coding ge