文档介绍：左旋甲状腺素钠片治疗妊娠期亚临床甲状腺功能减退的效果
[摘要]目的探究左旋甲状腺素钠片治疗妊娠期亚临床甲状腺功能减退(甲减)的临床效果。方法选取2016年1月~2017年6月在我院确诊为妊娠期亚临床甲减的孕妇70例,根据是否接受药物治疗分为治疗组和对照组,每组各35例。治疗组采用左旋甲状腺素钠片治疗,对照组未采用药物治疗,观察两组孕妇的甲状腺功能变化情况、妊娠结局及新生儿情况。结果治疗组孕妇治疗后甲状腺功能状况明显优于治疗组治疗前及对照组的甲状腺功能状况,差异有统计学意义(P中国论文网/6/view-
[关键词]左旋甲状腺素钠片;妊娠期;亚临床甲状腺功能减退
[中图分类号] [文献标识码] A [文章编号] 1674-4721(2017)12(b)-0035-03
[Abstract]Objective To explore the clinical effect of Levothyroxine Sodium Tablets in the treatment of subclinical hypothyroidism during From January 2016 to June 2017,70 pregnant women definitely diagnosed as subclinical hypothyroidism in our hospital were to acceptance of drug medication or not,they were evenly divided into treatment group and control the treatment group,Levothyroxine Sodium Tablets was used,while no drug medication in the control changes of thyroid function,pregnancy e,and the situation of newborns were observed in the two The thyroid function in the treatment group was significantly better than that before treatment,and that in the control group with statistical differences(),具有可比性。本研究经医院医学伦理委员会批准进行。
纳入标准:①单胎妊娠。②孕龄≤12周。③符合亚临床甲减的诊断标准[4]:(TSH)升高而血清游离甲状腺素(FT4)正常;;(TPOAb)阳性;以上三种情况单独出现一种即可确诊。④患者及家属自愿签署知情同意书。排除标准:①合并严重心脑血管、肝、肾相关疾病及精神疾病患者。②合并恶性肿瘤患者。③有甲状腺素药物过敏史或使用禁忌患者。④既往有高血压、糖尿病