文档介绍:Chapter 3
Pharmacodynamics
Contents
Contents
1、Basic action
2、Therapeutic effect
3、Adverse reaction
4、Dose- effect relationship
5、Mechanism of action
1、Basic action and Pharmacological effect
Drug action
Primary action
drug
acting
body
effect
second action
Two effect
Excitation:
Inhibition:
(兴奋)
(抑制)
正常
正常
强壮
烦躁不安
惊厥
死亡
Excitation
镇静
催眠
麻醉
回苏
麻痹
死亡
Inhibition
two characteristics :
1) specificity (特异性)
drug
2) Selectivity(选择性)
(tissue binding)
2. Therapeutic effect
the therapeutic goal.
Favorable to the normalization
of physiological, biochemical
functions.
治疗目标
therapeutic effects
1、Etiological treatment
2、Symptomatic treatment
急則治标,缓则治本
标本兼治,不可偏废也
治疗效果
1) Etiological treatment
Aims to eliminate pathogenic factor
. antibiotics----- microbes infection
2) Symptomatic treatment
Aims to allay or ameliorate symptom
. analgesics --- analgesia
对因治疗
对症治疗