文档介绍：中国组织工程研究与临床康复第 14 卷第 44 期 2010– 10– 29 出版
Journal of Clinical Rehabilitative Tissue Engineering Research October 29, 2010 ,
基因修饰嗅鞘细胞治疗脊髓损伤研究:可能成为首要的选择★
袁梦郎 1,2,呙金海 2,杨拯 1,张晓 1,郑渠 3
ic modified olfactory ensheathing cells for treating spinal cord injury: Possibility to be the
first choice
Yuan Meng-lang1,2, Guo Jin-hai2, Yang Zheng1, Zhang Xiao1, Zheng Qu3
Abstract
BACKGROUND: Previous studies demonstrated that olfactory ensheathing cells can play its role as target cells to carry target 1Department of
genes; however, this therapy still meets many problems. Experimental
Technology, 2Clinical
OBJECTIVE: To review the functions of ic modified olfactory ensheathing cells, and the problems existing between gene Medicine College,
modification and cell expression. 3Preclinical Medical
METHODS: Databases KI and PubMed were retrieved using key words of “olfactory ensheathing cells and spinal cord College, Chengdu
injury” both in Chinese and English. Basic research related treating spinal cord injury using ic modified olfactory Medical College,
Chengdu 610083,
ensheathing cells were included. Repetitive study or unrelated papers were excluded. Totally 29 documents were collected for Sichuan Province,
further study. China
RESULTS AND CONCLUSION: Olfactory ensheathing cells can secrete a variety of cytokines after spinal cord injury,