文档介绍:论文题目:阿尔茨海默病的研究现状概况
作者姓名:魏巍
指导老师:朱道立教授
专业班级:生物技术081
所在学院:生命科学学院
阿尔茨海默病的研究现状概况
【摘要】
阿尔茨海默病(Alzheimer disease,AD)是一种渐进性大脑退行性病变,是德国著名神经解剖学家和病理学家Alzheimer 于1907年首先描述,后人以其姓氏命名的。它是最常见的成年痴呆症,其发病率随年龄增长急剧增高。在欧美国家,其发病率在65岁的人群中为5%左右,而在85岁老年人中,其发病率则高达50%。由于AD患者伴有不同程度的记忆缺失、认知障碍,生活不能自理,不但严重影响患者本身的生活质量,还给家庭和社会带来沉重的负担。因此AD是当今公认的医学和社会学难题,已引起各国政府和许多研究人员的广泛重视。
【关键词】阿尔茨海默病,疾病病理,影响因素,治疗策略
【Abstract】
Alzheimer's disease (Alzheimer disease, AD) is a progressive degenerative brain disease, is a German anatomist and pathologist nerve Alzheimer first described in 1907, later generations named after its is the mon adult dementia, the incidence rate increased sharply with western countries, its incidence among people aged 65 and 5% of the elderly in 85 years, the incidence is as high as 50%.As the AD patients with varying degrees of memory loss, cognitive impairment, life can not take care of themselves, not only affected their quality of life of patients, returned to the family and society, a heavy AD is today recognized medical and social problems, has attracted many researchers governments and extensive attention.
【Key word】Alzheimer disease , Disease pathology , Factors , Treatment strategies
【正文】
Ⅰ.阿尔茨海默病概述
阿尔茨海默病(Alzheimer disease,AD)是一种伴有认知、行为和功能失常的进行性的神经变性疾病,是老年痴呆的一种最常见的形式。AD是1906年由德国神经病理学家AloisAlzheimer最先描述的。这是1例55岁的女性患者,该患者在生前已多年遭受严重的包括——记忆、