文档介绍：CD44v6 、VEGF、 CEA水平检测对良恶性胸腔积液鉴别的意义
(作者:___________单位: ___________邮编: ___________)
【摘要】目的探讨CD44v6、VEGF、CEA单项和联合检测对鉴别良恶性胸腔积液的价值。方法选取70名胸腔积液患者,其中良性疾病组患者35例,恶性疾病组患者35例。采用ELISA法检测胸腔积液CD44v6、VEGF、CEA 水平。结果在恶性疾病组中,CD44v6、VEGF、CEA的平均检测值分别为(±)ng/ml、(±)pg/ml和(±)ng/ml,在良性疾病组中CD44v6、VEGF、CEA平均检测值分别为(±)ng/ml、(±)pg/ml、(±)ng/ml。在单项检测中CD44v6、VEGF、%、%、%,%、%、%;在联合检测中,VEGF+ %,%;CD44v6+%,%;VEGF+ %,%;VEGF+ CD44v6+%,%。结论恶性疾病组胸腔积液CD44v6、VEGF、CEA水平分别明显高于良性疾病组,差异有显著性。单项检测中,VEGF和CD44v6有较高的敏感度和特异度,而在联合检测中,以VEGF+ CD44v6和VEGF+CEA的敏感度和特异度相对较高。刘志波(1977~),男,汉族,辽宁籍,青海大学医学院2005级研究生
【关键词】胸腔积液 CD44v6 VEGF CEA 联合检测鉴别诊断
Abstract Objective To observe the diagnostic value of CD44v6 ,VEGF and CEA in determination of benign or malignant pleural effusion. Methods Among 70 patients with pleural effusion, 35 patients suffered from benign disease and 35 patients suffered from malignant disease. The expressions of CD44v6, VEGF and CEA in pleural effusion were detected with ELISA technique. Results In the group of malignant diseases, the average value of CD44v6, VEGF and CEA were ±, ± and (±) ng /ml, respectively. In the group of benign disease, the average value of CD44v6, VEGF and CEA were