CRP CEA等指标检测在良恶性渗出性胸腔积液鉴别诊断中的价值.doc

文档介绍：CRP CEA等指标检测在良恶性渗出性胸腔积液鉴别诊断中的价值
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【摘要】目的分析胸腔积液患者胸水中C反应蛋白(CRP)、癌胚抗原(CEA)、β2微球蛋白(β2-MG)及触珠蛋白(HPT)四项指标水平,探讨多指标检测在胸腔积液鉴别诊断中的价值。方法将68例不同病因的渗出性胸腔积液分为良、恶性渗出液组二组,检测患者胸腔积液四项指标水平,并通过受试者工作特征曲线分析。结果二组胸腔积液患者CRP、CEA、β2-MG及HPT均有显著性差异(),%,%。结论胸腔积液CRP、CEA、β2MG及HPT水平检测对鉴别渗出性胸腔积液性质有较好的临床实用价值,联合检测CRP和CEA能提高对良恶性渗出性胸腔积液的敏感度、特异度。
【关键词】胸腔积液 C反应蛋白癌胚抗原β2微球蛋白触珠蛋白鉴别诊断
【Abstract】 Objective To explore the diferential diagnostic values of the levels of CRP, CEA, β2-MG and HPT in pleural effusion in paients with pleural effusion .Methods 68 cases with diferential diagnostic pleural effusion were divided
into benign exudative and malignant exudative , CEA
, β2-MG and HPT were detected in two groups. To evaluate the values of four indexes and union of
indexes in diagnosing the property of pleural effusion by receiver operating characteristic curve(ROC). Results CRP, CEA, β2-MG and HPT activity in benign exudative group were higher than thd other group significantly(). The union of CRP and CEA would impove the sensitivity to % and speciality to % in diagnosing exudative pleural effusion. Conclusion CRP, CEA, β2-MG and HPT are useful parameters for differential diagnosis of pleural testing of CEA and CRP are more valuable.
【Key Words】 Pleural Carity Effusion C-reactive p