半夏厚朴汤处方的药材特性和显微鉴定.doc

文档介绍：半夏厚朴汤处方的药材特性和显微鉴定
(作者:___________单位: ___________邮编: ___________)
【摘要】目的对中药半夏厚朴汤所用生药材进行药材品种特性与显微鉴定研究。方法首先对半夏厚朴汤所用的生药材进行品种性状鉴定,然后常规粉碎,过65目筛,在显微镜下观察组织特征。结果半夏厚朴汤所用药材均为药典规定品种。结论本项研究对半夏厚朴汤的质量鉴别和临床应用等提供了可靠依据。
【关键词】半夏厚朴汤;药材特性;显微鉴定
Study on the Character of the Medicianl Materials in Banxia Houpu Tang and the Micro-identification
Qin Qin, Chengdu Medical College, Chengdu, Sichuan Province 610083
ABSTRACT Objective To study the character of medicinal materials in Banxia Houpu Tang with micro- A variety traits identification was made to the medicinal materials in Banxia Houpu Tang, after the routine smashing of the materials, the powder through 65 mesh sieve were microscopically observed. Results The medicinal materials in Banxia Houpu Tang are measured up to China Pharmacopoeia (CP).Conclusions The study provides reliable basis for quality identification and clinical application of Banxia Houpu Tang.
KEYWORDS Banxia Houpu Tang character of medicinal material micro-identification
由于西药的抗抑郁效果有限、易产生耐药性和副作用明显等原因,使许多患者开始寻求植物药进行治疗。目前欧美国家抗抑郁植物药的消费量逐年上升,而且全球大的制药公司也已经开始从植物药中提取抗抑郁成分,期望研究出新型的抗抑郁药物。作为世界最大的植物药产地,中国的潜力巨大,中药抗抑郁面临巨大机遇。临床证明中药抗抑郁的疗效肯定、副作用小、不易产生耐药性,且价格低廉,表明采用中药抗抑郁是可行的。

半夏厚朴汤始载于张仲景《金匮要略》,是治疗痰气郁结型(俗称“梅核气”)的经典名方。该方由半夏、厚朴、茯苓、紫苏和生姜等五味中药组成,常用以治疗精神性疾病如抑郁症、焦虑症等[1],在日本也用此方治疗抑郁症、神经官能症抑郁状态、焦虑等[2]。王业民等发现[3],半夏厚朴汤提取物(AE)可显著地减少小鼠游泳和悬尾不动时间,并随着给药时间的延长而加强,且趋于稳定。其活性强