文档介绍：鲍曼不动杆菌分布及耐药性分析
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作者:周宁莉,张之烽,陈俊根
【摘要】目的了解临床鲍曼不动杆菌感染分布及耐药情况。方法对2006年1月—2008年12月临床标本中分离的938株鲍曼不动杆菌进行回顾性调查分析。结果鲍曼不动杆菌检出以痰标本居多。药敏结果显示鲍曼不动杆菌对常用抗生素耐药性逐年增加,其中头孢哌酮/舒巴坦耐药率最低,对其他多种抗生素耐药严重。特别值得注意的是鲍曼不动杆菌多重耐药菌上升迅速,且以ICU为主。结论临床对鲍曼不动杆菌引起医院感染应高度重视,应合理应用抗菌药物以减少多重耐药菌株的产生。
【关键词】鲍曼不动杆菌;耐药性;医院感染
Abstract: Objective To investigated the clinical infections distribution of obacter baumanii and its drug resistance. Methods A total of 938 A. baumannii strains clinically isolated from January 2006 to December 2008 was retrospectively analyzed. Results The A .baumannii isolates were mostly in sputum specimens. The drug susceptibility reports showed that its rate of drug resistance mon antimicrobial agents increased annually, of which the rate of drug resistance to cefoperazone/sulbactam was the lowest and was seriously resistant to many other antibiotics. It should be noted that the rate of A. baumannii strains exhibiting multidrug resistance were rapidl
y on the increase, particularly in ICU. Conclusion ial infections caused by A. baumannii should be emphasized. Antimicrobial agents should be rationally used so as to decrease the prevalence of strains with multidrug resistance.
Key words: obacter baumannii; drug resistance; ial infection
已换鲍曼不动杆菌为需氧非发酵革兰阴性杆菌,是条件致病菌,为医院内感染的重要机会性病原菌。随着免疫抑制剂和大量广谱抗菌药物的应用,该菌引起的感染特别是多重耐药菌株的感染有增加的趋势。为了解鲍曼不动杆菌的分布特点、耐药现状及趋势