文档介绍：慢性化脓性中耳炎分泌物病原菌的分离及耐药性分析
【摘要】目的研究慢性化脓性中耳炎的病原菌的分布及对抗生素的耐药情况。方法对115慢性化脓性中耳炎患者的脓性分泌物进行细菌培养,并对分离的病原菌进行药物敏感试验。结果 115例标本中分离培养出病原菌113株,以金黄色葡萄球菌(41株)和假单胞铜绿杆菌(22株)为主,其次为表皮葡萄球菌(14株),变形杆菌(10株),大肠埃希杆菌(6株)等。以金黄色葡萄球菌感染为主的革兰氏阳性菌对头孢类、喹诺酮类药物敏感性较高,以铜绿假单胞菌为主的革兰氏阴性菌对头孢类、喹诺酮类、磺胺类、氨基甙类较敏感。结论金黄色葡萄球菌、假单胞绿脓杆菌是慢性化脓性中耳炎的主要病原菌,两者对头孢类、喹诺酮类抗生素的敏感率均较高。
【关键词】化脓性中耳炎病原菌耐药性
【Abstract】 Objective To study the pathogenic bacteria separation of chronic suppurative otitis media and its resistance to antibiotic. Methods Secretion from 115 cases with chronic suppurative otitis media were cultured, and drug sensitivity tests were done to separated pathogenic bacteria. Results 113 strains pathogenic bacteria were isolated from the secretions of 115 cases. The main pathogenic bacteria were us aureus (41 strains) and pseudomonas aeruginosa (22 strains), followed by us epidermidis (14 strains), Proteus mirabilis (10 strains), Bacillus coli (6 strains), etc. Gram-positive bacteria infection, which resulted mainly from us aureus, was sensitive to cephalosporins and fluorquinolones. Gram-negative bacteria infection,which resulted mainly from Pseudomonas aeruginosa, was sensitive to cephalosporins, fluorquinolones, sulfamido and aminoglycosides. Conclusions us aureus and pseudomonas aeruginosa are main pathogens of chronic suppurative otitis media. Both of them are sensitive to antibiotics of cephalosporins and fluorquinolon