成人间活体肝移植术中罗库溴铵的药效学研究.docx

文档介绍：PHARMACODYNAMICEFFECTSOFROCURONIUMDURINGADULT-TO-parisonofPharmacodynamicsofRocuroniuminAdminstrationbyTarget-controlledInfusionverseinBolusObjectiveToinvestigatethepharmacodynamiceffectsofrocuroniumduringdifferentstagesofadult-to-adultlivingdonorlivertransplantation;andevaluatetheeffectsonneuromuscularblockadeofrocuroniuminbolusorbytarget-controlledinfusion(TCI)inpatientswithhepaticfailurescheduledforadult-to--fourpatientswererandomlyassignedintogroupIV(roupTCI(receivingrocuroniumbyTCI)-of-four(TOF),bloodroutine,,±±,whichwassignificantlylongerthanthatinpreanhepaticphase(±).Rocuroniumrequirementdecreasedsignificantlyinanhepaticphase(±·kg-1·min-±·kg-1·min-1,ingroupIVandgroupTCI,respectively)andinneohepaticphase(±·kg-1·min-±·kg-1·min-1ingroupIVandgroupTCI,respectively),comparedwiththatinpreanhepaticphase(±·kg-1·min-±·kg-1·min-1,ingroupIVandgroupTCI,respectively).,tothereperfusionandrearterializationofnewliver,-