文档介绍：瑞芬太尼用于鼻内窥镜手术麻醉临床研究
应俊, 朱晓红,卢忆梅,陈受琳
江西医学院第二附属医院麻醉科,江西南昌市330006
摘要:目的::40例行鼻内窥镜手术患者随机分为瑞芬太尼组和芬太尼组,每组20例。麻醉诱导采用静脉注射丙泊酚(2mg/kg)和瑞芬太尼(2ug/kg)或芬太尼(2ug/kg)。麻醉维持采用持续静脉泵注异丙酚(6mg/kg),.02ug/。观察术中血压、心率、麻醉深度、阿托品、麻黄素、乌拉地尔的使用量,麻醉苏醒及不良反应等情况。结果:两组诱导后收缩压(SBP)、舒张压(DBP)明显降低(P<),瑞芬太尼组心率明显减慢(P<)。麻醉维持期间,瑞芬太尼组患者血流动力学变化幅度显著小于芬太尼组(P<)。瑞芬太尼组清醒时间,拔管时间短于芬太尼组。结论:瑞芬太尼镇痛作用强于芬太尼,停止输注后其作用消退快于芬太尼。
关键词: 瑞芬太尼; 芬太尼; 鼻内窥镜手术; 麻醉,全身
To Study the Efection of Remifentanil Used For ESS
YING Jun, ZHU Xiao-hong, LU Yi-mei, CHENG Shou-ling
(.Department of Anesthesiolgy, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang 330006,China)
Abstract Objective: pare the efficary and safely of remifentanil with fentanyl used for ESS. Methods: 40 patients undergoing ESS were randomly assigned to remifentanil group or fentanyl group with 20 cases in each group. Anesthesia was induced with propofol(2mg/Kg) and either remifentanil (2μg/Kg) or fentanly (2μg/Kg), and was maintained with a continuous infusion of propofol (6mg/kg•min) and a continuous infusion of either remifentanil (•min) or fentanly (•min). Blood pressure (BP), heart rate (HR), depth of anesthesia, the dose of ephedrine, atropine, urapidil required during surgery, recovery profile of anesthesia and adverse reactions were observed. Results: Blood pressure wa