文档介绍：摘要—1—妊娠合并甲状腺功能亢进症的临床分析研究生:孜列·吉恩斯导师:阿布力克木·吐尔地副教授摘要目的:本研究对新医大一附院爱婴病房及计划生育科9年来对妊娠合并甲亢的孕妇临床资料进行回顾性分析,探讨患有甲状腺功能亢进症(Graves病)的孕妇孕前及妊娠期系统规律的治疗是否能减少妊娠并发症、降低胎儿的丢失率及改善母婴的结局。方法:回顾性分析我院2001年-2009年104例健康及妊娠合并甲亢(Graves病)的孕妇母婴的结局。将其分为三组,第一组(健康妊娠组):既往否认任何病史包括甲状腺功能亢进症;第二组(治疗满意组):既往有甲亢病史或妊娠期发现甲亢,经抗甲状腺药物治疗后甲状腺功能亢进症控制良好并监测甲功正常未复发者;第三组(治疗不满意组):既往有甲亢病史或妊娠期发现甲亢,经抗甲状腺药物治疗后甲状腺功能亢进症控制欠佳并监测甲功提示甲亢复发者。结果:(1)三组妊娠孕妇的年龄、病程及孕周之间相互比较,病程及孕周均有统计学差异(P<),年龄无统计学差异(P>);(2)三组之间妊娠结局的相互比较显示健康妊娠组无新生儿流产及窒息。治疗满意组新生儿流产及窒息较治疗不满意组低。治疗不满意组的新生儿体重及Apgar评分均低于其他两组有统计学差异(P<)。(3)三组之间妊娠并发症相互比较显示:健康妊娠组中无并发妊高症及甲亢危象,治疗满意组中无妊高症发生,甲亢危象发生率较治疗不满意组低。治疗不满意组发生甲亢及妊高症比率均高于其他两组有统计学差异(P<)。结论:妊娠合并甲状腺功能亢进症(Graves病)的孕妇通过早发现早诊断并且经过系统规律治疗可明显改善母亲及胎儿的预后。关键词:甲状腺功能亢进症;妊娠并发症;妊娠结局新疆医科大学医学硕士学位论文—2—Clinical analysis of plicated with Hyperthyroidism postgraduate: supervisor:assistant : To investigate whether the treatment in pregestational and gestational period can reduce the plications and the rate of fetal loss and improve the maternal and fetal es in women with hyperthyroidism (Graves disease) before pregnancy and during pregnancy. Methods: A retrospective study was conducted on 104 healthy pregnant women and pregnant women with hyperthyroidism in our hospital from 2001 to 2009. The therapy in pregestation and gestation period and the rate of fetal loss were analyzed. All women were divided into three groups: the first group (healthy pregnant women) denied any history of hyperthyroidism; the second group(well treated women) with hyperthyroidism history before pregnancy or during pregnancy who had received antithyroids during pregestational and gestational period and resulted euthyroidism without recurrence; the third group (unwell treated cases): who did not receive,presented late to the clinics with severe conditions and resulted thyroid dysfunction. Results: (1) Pregnancy age, duration and gestational age of three groups showed the course of disease and the gestational ag