文档介绍:Electrodeposition of chitosan/gelatin coating on titanium: physicochemical characteristics , cell attachment and proliferation Postgraduate : Zhang Zhen Supervisor : Prof. Wang Yining Introduction ? Titanium implant is widely used in dental/craniofacial implants. ? It is only passively integrated with bone and lack interaction with the surround tissue. severe bone loss restoration after tumor excision Titanium surface modification to enhance bone growth and Inhibit tumor Inhibit tumor growth growth ? Approaches of modification of the implant surface can be classified as physicochemical, morphologic, or biochemical. ? Chitosan can be used as a bioactive coating and mediate assembly of ponents. Chitosan drug carriers gene delivery tissue engineering bioactive coating extended to the base and sidewalls of microfluidic channels implant Traditional methods to deposit chitosan on titanium have drawbacks respectively . Chitosan can be electrodeposited at a Aurum surface It prompt us to deposit chitosan on titanium surface by electrodeposition . Advantage Electrodepositing chitosan Various ship NO couplant No acid remain simple controlled Low temperature According to our experiment result, cell attachment and proliferation were not good on chitosan Gelatin is blended with chitosan to improve the biological activity . Chitoan Gelatin Chitosan gelatin Gelatin can enhance cell attachment and proliferation Objectives