文档介绍：2012年第20卷合成化学 V0l·20,2012 第5期,591。595 Clli啷e Jolmlal llemi8卸 No·5,591_595 ·快递论文· 1-[3’.(4”.甲氧基苯基)一5’.甲基异噫唑4’-甲酰基]_4- 芳基氨基硫脲及其衍生物的合成阿布拉江·克依木1,阿娜姑-托合提1,刘方明2 (,新疆乌鲁木齐830046; ,浙江杭州310036) 摘要:以3,(-5一甲基异嗯唑_4-基).4- 芳基氨基硫脲(3a一3c);3在不同条件下经关环反应制得含有3,5-二取代异嚼唑的2一芳氨基噻二唑(4a- 4c),(5a一5c)和3.[3’.(4”.甲氧基苯基)-5’-甲基屏嗯唑4’-基)-4-芳基一l,2,(6a。6c);6与碘甲(乙)-5-[3’一(4叱甲氧基苯基)_5’-’一基]-3-甲(乙)硫基一 1,2,(7a一8c),其结构经1H NMR,m,MS和元素分析表征,其中4,5,7和8未见文献报道。关键词:异嗯唑;芳氨基硫脲;1,3,4-噻二唑;1,3,4一嘻二唑;烷硫基-1,2,4一三唑;合成中图分类号:0626 文献标识码:A 文章编号:10Q5-1511(2012)05JD591硝 Synthesis of1-[37一(4Ⅳ-Metho珂phenyl)-5’-metllylis嘞zme_4 7- f;嗍myl]4一ary¨埘oselIlicarbazides and ItsDeriVatives KEYuME Ablaj锄1, ANAGu Tu矗觚1, uuF锄g-IIlin92 ( Chemi8try EngineeriIlg,x蜘i趾gUIIive玮毋,u咖qi 830046,Clli曲; 0f MaterialB,chemi8田蛐dChe毗a1 En昏n∞血g,H蚰gdl眦No瑚nalUlliV啪毋,H衄弘hou 310036,ClliIIa) Ah打act:Key intemledi8te,l一(3-p—-medlyu∞x踞0le4一y1)4-耐nliosemicarb商d∞(3a一3c),were prepared by吐le reaction of3,5-di鲫【bs劬ted i∞x舷01e一4-fom删driziIle widlaryli一∞,3,4mliadi啪le(4a一4c),l,3,4-ox础azole(5a一5c)and nlecorresponding 5- metll)d/etlIyltlliotria趵le(6a一6c)were syntllesized by出e cycli翻don 0f3in憾rent re∞tion condi— ∥etlIyldli埘踟le deri训ves(7a一8c)were syntlle8izedby dlereac妇of 6widlMeI orEⅡ.nes咖ctures were characteri跹dby 1HNMR,IR