文档介绍:A New Strategy for Enhancement Curdlan Biosynthesis in
Alcaligenes faecalis by Activating Gene Expression
1,2 1 1 1 1
Zhang Hongtao , Zhan Xiaobei* , Zheng Zhiyong , Wu Jianrong , Chen Dingqiang
1
Affiliation: The Key Laboratory of Industrial Microbiology, 2 Glycoscience laboratory, faculty of medicine, Northwick
Ministry of Education, Jiangnan University, wuxi, China park campus, imperial college London, HA1 3GX,
Address: 1800 Lihu Road, Wuxi, 214122, P. R. China London, Great British
*E-mail: xbzhan@
Abstract— Curdlan (β−1,3−glucan) is a kind of exopoly- eukaryotes and are extracted from cereals, mushrooms,
[8]
haride excreted by bacteria and has the ability of seaweed, and yeasts . Because the extraction and purification
improvement of immune and anticancer. It has potential method of curdlan is cheaper than other fungal β-glucan, so
values as medical material in medicine field. Many many researcher are focusing on improving curdlan production
with various factors, for example: UDP, UTP, uridine and
researchers began to focus on the interaction of curdlan [9] [10]
and immune signal protein for finding the detail uracil addition , phosphate concentration , carbon source,
oxygen supply [11], pH[12] and anism concentration .
mechanism of its bioactivity. The aim of this work was to
investigate the effect of antibiotics and ammonia add