文档介绍：Network System with Signal Integration of
ANDN Gate
Ke Ren, Yun Tang
Department of Mathematical Sciences
Tsinghua University
Beijing, 10084,
Abstract—In the recent years works theory as a repressilator. In the system, gene luxl from the LuxI/LuxR module
powerful tool has been used in the study of such hot topics as , first synthesizes a small molecule S. Both S and LuxR then form a
systems biology and optimization of traffic system. This article hetero-plex. The dimmer of Y and plex
co-regulate the target gene, thus carrying out a function of a
focuses on work system consisting of famous repressilators
cis-regulatory module (CRM), referring (I).
coupled by quorum sensing, where intracellular and extracellular
signals are integrated in an ANDN logic manner. A local Theoretically, a CRM may correspond to eight possible logic
operations, AND, OR, ANDN, ORN, NAND, NOR, XOR and
synchronization criterion is established, where the cis-regulatory
EQU [4]. Limited by the specific structure of the repressilator,
input function of ANDN response plays a key role. Moreover, the however, there are only four kinds of logic modes, ANDN, ORN,
local result is extended to the global case through the specific NOR and NAND, each of which integrates intracellular and
structure of work. extracellular signals by endogenous and exogenous