文档介绍：Anti-tumor effect and its mechanism of aria
segetalis on mouse inoculated H22 solid carcinoma
Yue-Ying GAO, Li-Ying QIU *, Xiao-Xing KANG, Hua Wang, Ling –Yan Liu,Lei FENG, , Jian JIN,
School of medicine and pharmaceutics
Jiangnan University
Wuxi 214122,
Abstract: AIM aria segetalis was reported anti-tumor action CONCLUSION aria segetalis can improve the the quality of
in vitro. In this study, the effect and mechanism of inhibiting tumor life on mice invased by tumor, and inhibit the growth of tumor. The
growth and improving the quality of life of aria segetalis on mechanisms were likely due to inhibiting the angiogenesis, and
mouse inoculated H22 solid carcinoma were investigated. inducing the apoptosis of tumor cells and vascular endothelial cells.
METHODS The solid carcinoma model of mouse was made by Keywords : aria segetalis; apoptosis; tumor
H22 cells subcutaneous injection and they were divided into four angiogenesis;H22 solid carcinom mouse
groups including model control group, 1mg/kg treatment dose,
treatment dose and 5mg/kg treatment dose groups of I. INTRODUCTION
aria ig treatment for 10 days,the mice were
In the past three decades, tremendous advances have been
killed,and the inhibited rate of tumor growing was calculated. The
made in developing anti-cancer drugs. Herceptin, Tamoxif