文档介绍：I 摘要乙酰苯胺即退热冰,学名 N-苯(基)乙酰胺, 白色有光泽片状结晶或白色结晶粉末,是磺胺类药物的原料,可用作止痛剂、退热剂、防腐剂和染料中间体,由苯胺和冰醋酸通过酰化反应制得。本设计讨论了乙酰苯胺大批量生产的方法、合成工艺路线,乙酰苯胺生产车间的设计以及绘制车间流程、立面等多张 CAD 图纸,并针对乙酰苯胺车间酰化岗、减压蒸馏岗进行了物料衡算、热量衡算以及设备衡算。关键词:乙酰苯胺;退热冰;生产;车间设计 Abstract N-Acetylaniline, a scientific name of N-benzene (phenyl) acetamide, glossy sheet of white crystal or white crystalline powder, isa sulfa drug raw materials, can be used as analgesics, antipyretic agents, preservatives and dyes intermediates from aniline and glacial acetic acid through the acylation reaction. Discussed the design of ice-cooling method of high-volume production, synthesis of line, ice-cooling design and production process mapping workshop, more than one facade, such as CAD drawings, and ice-cooling plant for acylation Kong, vacuum distillation Kong conducted a material balance, heat balance and the balance device. Key word: cooling ice; acetanilide; production; plant design II 目录摘要.......................................................................................................... I Abstract ................................................................................................... II 目录..................................................................................................... III 1 研究内容的目的及意义......................................................................... 1 2 国内外乙酰苯胺市场情况..................................................................... 2 3 乙酰苯胺合成工艺的比较..................................................................... 4 乙酸酐法合成乙酰苯胺................................................................. 4 催化控温法合成乙酰苯胺............................................................ 4 其他合成乙酰苯胺的方法............................................................ 4 总结比较合成方法........................................................................ 4 4 乙酰苯胺合成工艺................................................................................. 6 工艺流程................................................................