文档介绍：Chapter 9 Diseases of Respiratory System
Department of Pathology
China Medical University
Wang Enhua
Infection of respiratory tract
Acute tracherobronchitis
Acute bronchiolitis
Pneumonia
Acute catarrhal tracheobronchitis. The inflammatory exudate on the mucosal surface is chiefly a stringy, basophilic mucus only scantily mixed with leukocytes.
Acute suppurative tracheobronchitis. There is a significant element of leukocytic infiltration.
Acute ulcerative tracheobronchitis. The inflammatory reaction is more intense, with necrosis of the mucosa in areas, it constitutes an ulcerative form.
Acute tracheobronchitis
The bronchioli mucosa is hyperemia and swelling with a lymphomonocytic and leukocytic infiltration of the submucosa panied by overproduction of mucous secretions.
Bronchiolitis obliterans is characterized by polypoid masses anizing inflammatory exudates and granulation tissue extending from alveoli into bronchioles
Acute bronchiolitis
broadly defined: any infection in the lung
histologic spectrum-vary from
a fibrinopurulent alveolar exudate —
acute bacterial pneumonia
bronchopneumonia
lobar pneumonia
mononuclear interstitinal infiltrates—
viral/atypical pneumonias
granulomas/ cavitation — chronic pneumonias
Pneumonia
1. Bacteria pneumonia(1) Lobar pneumonia
an acute bacterial infection of a large portion of a lobe or of an entire lobe
fibrinous inflammation
Symptoms: abrupt onset, high fever, shaking chills, pleuritic chest pain, a productive mucopurulent cough ( “rusty” sputum )
Etiology
pathogens: us-pneumoniae,
pneumobacillus
inducing factors: cold, excessive tired, anethesia
Pathogenesis
bacteria---alveoli---proliferate , capillary dilate, serious exudates---kohn’s pores---spreading entire lobe
Pathologic changes
(1)congestion stage:1st-2nd days
the outpouring of a protein-rich exudate into alveolar spaces and rapid proliferation of bacteria.
gross heavy, red, boggy
LM
alveolar wall: cap. dilate,