文档介绍：Oncology
Treatment in 
Denamark
Lars Krag Møller
Dept. of Development and Quality  October 2014
and  
Dept. of Obstetrics and Gynecology
Background 
Gynecologic cancer in Denmark
• From 52 gynecologic departments to five in 20 
years
•> 5 years since we operated advanced cancer at 
Hvidovre Hospital
• The following treatment plan is grounded in the 
guidelines for gynecologic cancers in Denmark 
and through diskussions with Gynecologist and Dr
of Science Lene Lundvall, Lian Ulrik and Jan 
Blaakær. For further information, they can be 
consulted
/ is worth a visit
Endometrial cancer
Guidelines was written by a team with 
representativs from 
• The College of Clinical Oncology
• The College of Pathology and Cytology
• The College of Obstet and Gyn in Denmark
ges/retningslinier/Corpuscancer/E
ndometriecancer_2010‐
Endometrial cancer
Incidens of endometrial cancer 
in Denmark (5 mill inhabitants))
• 600 new cases pr year in DK (unchanged last 20 
years)
• Incidens has doubled from 1943 to 1980
• The 6. mon cancer 
• Incidens: 13 out of 
• Five years survival
– STAGE I: >90 %
– Stage II: 60%
– Stage III: 40% 
Endometrial cancer
Immage diagnostics
Hosptial
Endometrial cancer
Risk factors
• Continous bination therapy
reduces the risk
• Sequential bination therapy
oestrogen/gestagen or Tamoxifen, elevats the 
risk of endometrial cancer
• Adipositas, PCO, Diabetes Mellitus
Endometrial cancer
Pathology
• CIS – compex hyperplasia with atypia
– 17‐52% of all ec
• Endometrial Adenocarcinoma
– 89%
• as
– 3‐4%
• Hyperplasia witout atypia is not cancer, 
evetually gestagene
Endometrial cancer
Calssification accordning to 
FIGO 2009 (new has been developed)
Grade
• Grad 1: 
– High differentiation: < 5 % non‐plano, non‐
morular, solid tumor 
• Grad 2
– Middle high differentiation: 6‐50 % non‐p