可显影软腭植入材料纤维化实验研究.pdf.pdf

文档介绍：生物医学工程与临床年月第卷第期
96-- 2010 3 14 2 BME & Clin Med, March 2010,,
基础研究
· · doi: .1009-
可显影软腭植入材料纤维化实验研究
汪建张天翔陈亮付晓燕
, , ,
比较自行研制的可显影软腭植入材料与软腭植入材料即的纤维化效果普通大
摘要: 目的 HA-P Pillar ( PET) 。方法
白兔只分为组第一组肌层内植入根另一组植入材料于术后第天组分别处死实验
20 2 , 1 PET, HA-P , 7、15、30、60、90 2
动物只将埋植材料连同周围组织完整取出制成标本并做石蜡切片行组织学检查然后采用图像分析软件对纤维层厚度
2 , , ,
进行测量两组材料纤维层厚度均随时间延长而增加早期纤维化程度更好术后实验组纤维层厚度为
。结果, PET , 90 d
对照组为两组差异无统计学意义自行研制的可显影软腭植
( ± ) μm, ( ± ) μm, (P > )。结论 HA-P
入材料与材料有相似的纤维化效果
Pillar 。
软腭植入聚乳酸羟基磷灰石聚对苯二甲酸乙二酯纤维化
关键词: ; ; ; ;
中图分类号: 文献标识码:A 文章编号:1009-7090(2010)02-0096-04
Experimental study on displayed palatal implants fibrosis in rabbits WANG Jian, ZHANG Tian-xiang, CHEN Liang,
FU Xiao-yan (Department of Otolaryngology, General Hospital of Guangzhou mand of PLA, Guangzhou 510010,
Guangdong, China)
Abstract: Objective pare the fibrosis effects of polyethylene terephthalate(PET) and HA-P implants on the histologic
structure of the palatal tissue in rabbit model. Methods Twenty rabbits were implanted PET and HA-P in muscle divided into 2
groups respectively. The animals were sacrificed after implantation at 7 days, 15 days, 30 days, 60 days and 90 days, 2 animals for
each time. Specimens were collected for HE staining. Image Tool for Windows version was applied to measure the thickness of
caps