文档介绍：摘要
本毕业设计的任务是设计年产10亿片苯磺酸左旋氨***地平的片剂车间工艺设计。设计深度为医药工程的初步设计。根据《药品生产质量管理规范》和我在湖北远大制药集团有限公司的毕业实****车间实践,联系我们所学的专业课各方面知识,参照了《药物制剂》、《药剂学》、《药物分析》、《化工原理》、《制药工程》、《化工工艺设计手册》、《制剂单元操作》、《制剂工程设计》、《制药工业的洁净与空调》、《药物制剂工程》等文献,严格按照2010年版GMP、《GMP实施指南》、《医药工业洁净厂房设计规范》、《建筑设计防火规范》、《建筑给排水规范》、《工业企业照明设计标准》、《工业企业采暖通风和空气调节设计规范》等多种设计规范和管理规范进行,在老师们得帮助下共同努力成功完成了本次毕业工程设计。经过准确的计算和筛选,我设计了合理的工艺流程路线,设备选型,车间布置设计。此外,我们还做了严格的物料衡算、公共系统消耗、工艺管道计算。为了达到GMP的标准,我们还在生产制度,消防及卫生、劳动安全、“三废”处理、环境保护等多方面设计了详细的设施和制度。这次设计是专业知识和工程设计实践的完美结合,整个过程中得到了老师和同学们的大力支持和帮助,它培养了我们分析和解决工程中实际问题的综合能力,提高了应用AUTOCAD绘制工程图纸的能力和,增强了在中英文文献中收集有用信息的能力,同时也培养了我们的集体和团队的合作精神。
关键词:片剂;苯磺酸左旋氨***地平;车间设计;
Abstract
This graduation project duty is designed depth for medicine project preliminary design. According to <Drugs Production Quality control Standard> and we in Wuhan Grand Pharmaceutical thegraduation fieldwork workshop practice, relates the professionalcourse various aspects knowledge which we studies, referred to<Medicine Preparation>,<Pharmaceutics>, <Medicine Analysis>,<Chemical industryTechnological design Handbook>, <Preparation Unit operation>,<Preparation Engineering design>,<Medicine Preparation Project> and so onthe literature, Strictly according to GMP, pleted this graduation engineering design after our group fourmembers joint effort esses. After the putation and screening, we have designed thereasonable technical process route, the equipment shaping, theworkshop arrangement design. In addition, we also did have been strict the public system consumption、the process putation. In order to achieve GMP the standard, we also in theproductive system, the fire prevention and the health、the laborsafety、three wastes processing, the environmental protectionand so on have variously designed the detailed facility and thesystem. This design is the specialized knowledge and the engineering designpractice perfect union, it trained us to analyzewith the solution project in the actual problem synthesizing capacity,enhanced has applied the AUTOCAD plan project